Xu Meng Selected Research

monoclonal antibody RN168

1/2020

Model-Based Characterization of the Pharmacokinetics, Target Engagement Biomarkers, and Immunomodulatory Activity of PF-06342674, a Humanized mAb Against IL-7 Receptor-α, in Adults with Type 1 Diabetes.

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Xu Meng Research Topics

Disease

22	Atrial Fibrillation 02/2021 - 07/2005
9	Heart Failure 01/2021 - 09/2006
5	Hemorrhage 01/2021 - 09/2009
4	Cardiogenic Shock 01/2022 - 12/2009
4	Hypertension (High Blood Pressure) 01/2021 - 04/2019
4	Thrombosis (Thrombus) 01/2021 - 07/2008
3	Fibrosis (Cirrhosis) 01/2018 - 05/2015
3	Necrosis 12/2017 - 01/2016
3	Neoplasms (Cancer) 09/2017 - 01/2010
3	Cardiac Arrhythmias (Arrythmia) 08/2014 - 09/2006
3	Gastroesophageal Reflux (GERD) 08/2011 - 06/2010
2	Paraganglioma (Paragangliomas) 01/2022 - 01/2021
2	Heart Valve Diseases (Valvular Heart Disease) 10/2021 - 01/2021
2	Tricuspid Valve Insufficiency (Insufficiency, Tricuspid Valve) 10/2021 - 09/2020
2	Hypertrophic Cardiomyopathy (Hypertrophic Obstructive Cardiomyopathy) 01/2021 - 04/2012
2	Stroke (Strokes) 09/2020 - 01/2019
2	Pulmonary Hypertension 04/2020 - 09/2002
2	Prolapse 04/2020 - 02/2010
2	Hyperaldosteronism (Conn Syndrome) 01/2020 - 12/2018
2	Aortic Valve Stenosis (Aortic Stenosis) 10/2019 - 05/2019
2	Body Weight (Weight, Body) 01/2018 - 12/2014
2	Takayasu Arteritis (Arteritis, Takayasu's) 08/2017 - 07/2016
2	Myocardial Infarction 05/2017 - 09/2009
2	Aneurysm (Aneurysms) 05/2017 - 12/2008
2	Neoplasm Metastasis (Metastasis) 01/2017 - 01/2010
2	Hypertrophy 01/2017 - 04/2012
2	Atrial Flutter (Flutter, Atrial) 12/2016 - 01/2013
2	Rheumatoid Arthritis 12/2016 - 01/2016
2	Inflammation (Inflammations) 08/2015 - 01/2013
2	Heart Diseases (Heart Disease) 02/2014 - 11/2008
2	Skeletal Abnormalities Mandibular Hypoplasia Auditory Canal Atresia Short Stature 04/2011 - 12/2010
2	Congenital Heart Defects (Congenital Heart Defect) 09/2009 - 03/2007
1	Pheochromocytoma 01/2022
1	Sleep Initiation and Maintenance Disorders (Insomnia) 12/2021
1	Right Ventricular Hypertrophy 01/2021
1	Pneumonia (Pneumonitis) 01/2021
1	Heart Arrest (Cardiac Arrest) 01/2021
1	Alzheimer Disease (Alzheimer's Disease) 01/2021
1	Adenomyosis 08/2020
1	Dysmenorrhea (Menstrual Pain) 08/2020
1	Adrenocortical Adenoma (Disease, Conn's) 07/2020
1	Eosinophilia 01/2020
1	Type 1 Diabetes Mellitus (Autoimmune Diabetes) 01/2020
1	Dehydration (Water Stress) 01/2020
1	Essential Hypertension 04/2019
1	Knee Osteoarthritis 03/2019
1	Osteoarthritis 03/2019

Drug/Important Bio-Agent (IBA)

5	Therapeutic UsesIBA 01/2020 - 04/2009
5	MicroRNAs (MicroRNA)IBA 09/2017 - 07/2012
4	Proteins (Proteins, Gene)FDA Link 12/2017 - 05/2013
3	Warfarin (Coumadin)FDA LinkGeneric 01/2021 - 01/2019
3	Pharmaceutical PreparationsIBA 12/2019 - 08/2011
3	Pantoprazole (Protonix)FDA LinkGeneric 08/2011 - 06/2010
2	Antihypertensive Agents (Antihypertensives)IBA 01/2020 - 04/2019
2	Blood Glucose (Blood Sugar)IBA 01/2017 - 09/2006
2	GadoliniumIBA 01/2017 - 01/2017
2	Methotrexate (Mexate)FDA LinkGeneric 12/2016 - 01/2016
2	Rituximab (Mabthera)FDA Link 12/2016 - 01/2016
2	Biosimilar PharmaceuticalsIBA 12/2016 - 01/2016
2	Messenger RNA (mRNA)IBA 08/2015 - 05/2015
2	Anti-Arrhythmia AgentsIBA 08/2014 - 01/2013
2	Irbesartan FDA LinkGeneric 04/2011 - 10/2010
1	CatecholaminesIBA 01/2022
1	PotassiumIBA 01/2021
1	CytokinesIBA 01/2021
1	urinastatin (MR 20)IBA 01/2021
1	Octreotide (Sandostatin)FDA LinkGeneric 01/2021
1	biapenem (L 627)IBA 01/2021
1	NucleotidesIBA 01/2021
1	Analgesics (Analgesic Drugs)IBA 08/2020
1	Adrenal Cortex Hormones (Corticosteroids)IBA 01/2020
1	Polymethyl Methacrylate (Sol)IBA 01/2020
1	Mannitol (Osmitrol)FDA LinkGeneric 01/2020
1	TitaniumIBA 01/2020
1	Sugar AlcoholsIBA 01/2020
1	Interleukin-7 Receptors (Interleukin 7 Receptor)IBA 01/2020
1	yttria (yttrium oxide)IBA 01/2020
1	AnticoagulantsIBA 01/2020
1	Biomarkers (Surrogate Marker)IBA 01/2020
1	ElectrolytesIBA 01/2020
1	Sorbitol (Yal)FDA Link 01/2020
1	monoclonal antibody RN168IBA 01/2020
1	Mineralocorticoid Receptor AntagonistsIBA 01/2020

Therapy/Procedure

12	Therapeutics 01/2022 - 10/2008
8	Radiofrequency Ablation 05/2011 - 07/2005
5	Extracorporeal Membrane Oxygenation 05/2015 - 12/2007
4	Minimally Invasive Surgical Procedures 02/2021 - 07/2008
4	Coronary Artery Bypass (Coronary Artery Bypass Surgery) 08/2017 - 03/2007
4	Cardiopulmonary Bypass (Heart-Lung Bypass) 12/2016 - 12/2008
4	Maze Procedure 12/2016 - 03/2007
3	Operative Surgical Procedures 01/2021 - 09/2005
3	Catheter Ablation 09/2020 - 01/2011
3	Cardiac Resynchronization Therapy 11/2013 - 07/2008
2	Heart Transplantation (Grafting, Heart) 01/2021 - 09/2009
2	Catheters 09/2020 - 01/2011
2	Adrenalectomy 07/2020 - 01/2020
2	Transcatheter Aortic Valve Replacement 10/2019 - 05/2019
1	Acupuncture Points (Acupuncture Point) 12/2021
1	Induced Heart Arrest (Cardioplegia) 01/2021
1	Artificial Respiration (Mechanical Ventilation) 04/2020